Healthy leg veins contain valves that open and close to assist return of blood to the heart. Venous reflux disease develops when the valves that keep blood flowing out of the legs and back to the heart become damaged or diseased. As a result, vein valves will not close properly, leading to symptoms of:
• Pain and swelling
• Leg heaviness, fatigue, and cramping
• Itching and burning
• Varicose veins
• Skin changes and leg ulcers